Nutrition and chemoprevention controversies

Trending Cardiovascular Nutrition Controversies.

The potential cardiovascular benefits of several trending foods and dietary patterns are still incompletely understood, and nutritional science continues to evolve. However, in the meantime, a number of controversial dietary patterns, foods, and nutrients have received significant media exposure and are mired by hype. This review addresses some of the more popular foods and dietary patterns tha...

Controversies in Chemoprevention of Colorectal Cancer with Ursodeoxycholic Acid

Colorectal cancer (CRC) is one of the most common cancers among men and women in western countries. Both in vitro and in vivo data strongly suggest that ursodeoxycholic acid (UDCA), a tertiary bile acid found naturally in low concentrations in humans may protect against CRC. Human studies also suggest that UDCA inhibits tumor development in high-risk subjects and inflammatory bowel disease (IBD...

Optimizing child-focused nutrition policies: considerations and controversies.

Updates and Controversies in the Rapidly Evolving Field of Lung Cancer Screening, Early Detection, and Chemoprevention

Lung cancer remains the leading cause of cancer-related death in the United States. Cigarette smoking is a well-recognized risk factor for lung cancer, and a sustained elevation of lung cancer risk persists even after smoking cessation. Despite identifiable risk factors, there has been minimal improvement in mortality for patients with lung cancer primarily stemming from diagnosis at a late sta...

Controversies in the Mechanism of Total Parenteral Nutrition Induced Pathology

Over 30,000 patients are permanently dependent on Total Parenteral Nutrition (TPN) for survival with several folds higher requiring TPN for a prolonged duration. Unfortunately, it can cause potentially fatal complications. TPN infusion results in impairment of gut mucosal integrity, enhanced inflammation, increased cytokine expression and trans-mucosal bacterial permeation. It also causes endot...